Staff Research Associate

Apply by: July 5, 2024

Work as part of a research team under the direction of the PI studying the population genomics of mosquito vectors of human and animal diseases. These include Anopheles gambiae s.l., the principal vector of human malaria in sub-Saharan Africa and the mosquito, Aedes aegypti, which is the vector of dengue and Zika viruses and is an invasive mosquito species recently established in the state of California. Duties include molecular laboratory work (DNA extractions, PCR, Gel Electrophoresis, NGS library preparation, MassArray multiplex assays, etc.) and basic laboratory maintenance such as re-stocking consumable lab supplies and cleaning re-useable supplies. The lab assistant will have the opportunity, if desired, to travel to field sites in São Tomé & Príncipe (west Africa) and, possibly, other sites in Africa to assist with Anopheles mosquito collections, processing, extraction, and laboratory setup. 

Key Responsibilities 

• 90% - APPLIED RESEARCH
  • Conduct laboratory experiments performed on > 4000 samples year under BSL2 conditions, including DNA extraction and quantification and PCR.
  • DNA quality control via Qubit, Nanodrop, and Tapestation 4200.
  • Analyze extracted samples using a wide array of gel-based assays using both conventional gel electrophoresis rigs and e-gel rigs.
  • Assess DNA samples for quantity and quality using an Agilent Technologies TapeStation and genotyping using a MassArray instrument and the associated software to score individual genotypes; proof-reading chromatographs and entering data into a web-based database.
  • Preparation of libraries for whole genome sequencing, conducting quality control assays on these libraries and preparation of libraries for sequencing by the DNA core facility.
  • Enter and maintain data in online project databases and spreadsheets.
  • Assist with ongoing mosquito-based research projects involving mosquito rearing or non-target species.
  • Assist with organizing incoming samples from field sites to ensure they are labeled, sorted, and entered into the online database correctly
  • Communicate results and relevant updates in weekly lab meetings.
• 10% - LABORATORY MAINTENANCE AND TRAINING
  • Assisting in the training of undergraduates participating in the undergraduate research scholar program. Act as primary mentor to at least one undergraduate per year, helping them design, carryout, analyze, and present, their own research project.
  • Assist with ordering supplies, maintaining laboratory inventory and equipment, organization of travel supplies, lab benches, and work space, etc. 
  • Assist in writing reports/publications including formatting of articles and use of reference manager computer program.

Minimum Qualifications

• BS in biological sciences or an equivalent combination of education and experience and basic computing skills with knowledge of Word, Excel and PowerPoint
• Experience (through employment or coursework) with DNA analytical methods (e.g. extraction, PCR, electrophoresis, sequencing)
• Mathematical skills and knowledge to perform routine laboratory calculations for molecular biology applications
• Solid understanding of basic genetics and molecular biology.
• Strong organizational skills and excellent interpersonal and communication skills to work with others in a collegial team environment
• Skills to follow detailed instructions on the conduct of laboratory protocols and understanding of the importance laboratory cleanliness and contamination prevention.
• Willingness to adapt to a rapidly changing work environment and respond to unforeseen challenges and delays while remaining productive

Preferred Qualifications

• Knowledge and/or experience with entomology or related organismal biology
• Background in population genetics, genomics and/or bioinformatics
• Computer programming skills
• Knowledge of basic laboratory equipment including autoclave, PCR machines, laboratory freezers, etc.

Work Environment

• Work flexible schedule including rotating weekends and occasional holidays.
• Work in areas where hazardous materials are present.
• Work in open cubicle area where noise from others is present.
• The Smoke and Tobacco Free Environment policy is intended to provide a healthier, safer, and more productive work and learning environment for the entire UC community. The University of California prohibits smoking and tobacco use at all University owned or leased properties, or facilities operated by UC staff or faculty. Smoking and tobacco use are strictly prohibited in indoor and outdoor spaces, parking lots, residential space, and University vehicles. https://ucdavispolicy.ellucid.com/documents/view/271

HOW TO APPLY

1. Apply at UC Davis careers site: https://www.ucdavis.edu/jobs 
2. Search Staff Job ID: 70478
3. Sign In to access your account or select the New User link to create one. 
4. Review the job description and select the Apply button to begin your application.